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With so many options for suppressing appetite for weight loss, what is the best weight loss medication?
The answer to this question depends on your medical situation, preferences, and the experience and training of the prescribing weight loss physician. Having said that, let us review the various weight loss medications in the order of their effectiveness.
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Watch is a combination weight loss medication that was approved as the brand name Qsymia in 2011 by the United States Food and Drug Administration. Phentermine is an amphetamine based, and traditionally, one of the most used weight loss medication. When combined with a low dose of a neuropathy, anti-seizure type medication that is commonly used to treat migraines etc. called Topiramate, there is significant synergy. With this synergy, the expected weight loss with the combination of Phentermine and Topiramate is higher than the sum of the expected weight loss from each of the two individual components used separately, hence the synergy in curbing appetite and helping one lose weight. Partly due to the Topiramate, this combination not only helps suppress the appetite but also takes away cravings for foods, such as carbohydrate, sugar or salt cravings thus reducing food intake and leading to effective and fast weight loss in most patients.
Who should consider Phentermine and Topiramate for losing weight?
Any adult who is obese defined as a body mass index of 30 or more, or any overweight person with a body mass index of 27 or more with one or more weight related medical problems such as high blood pressure, cholesterol problems, sleep apnea, diabetes etc.
Interestingly, this is one of the few weight loss medications that is FDA approved not only to help one lose weight but also to maintain weight as obesity is now recognized as a chronic medical problem that needs long term medical management just like high blood pressure, high cholesterol or other life style related medical conditions.
This novel combination weight loss medication, Phentermine and topiramate should be used along with a reduced calorie diet and exercise plan.
What is Phentermine and how does it work for weight loss?
Phentermine is in a class of medications called anorectics. It works by decreasing appetite.
What is Topiramate and how does it work for weight loss?
Topiramate is in a class of medications called anticonvulsants. It works by decreasing appetite and by causing feelings of fullness to last longer after eating.
How should Phentermine and Topiramate be used?
Phentermine and topiramate is usually taken with or without food once a day in the morning and taken at around the same time every day.
Dose titration of Phentermine and Topiramate
It is recommended to start phentermine and topiramate at a lose dose and increase the dose after 14 days. If need be, the dose can be further titrated at regular intervals until the most effective combination is reached, not to exceed the maximum recommended dose of Phentermine 37.5 mg daily.
When will I know if Phentermine and Topiramate are working for me?
After you take this combination medication for 12 weeks, the weight loss doctor will check to see how much weight you have lost. If you have not lost a certain amount of weight, the weight loss doctor may tell you to stop taking phentermine and topiramate or may increase the dose.
After you take the new dose of Phentermine and Topiramate for 12 weeks, your weight loss doctor will check to see how much weight you have lost. If you have not lost a certain amount of weight, it is not likely that you will benefit from taking phentermine and topiramate, so your doctor will most likely tell you to stop taking the medication.
Control of appetite with Phentermine and Topiramate
Phentermine and topiramate will help control your weight only as long as take the medication. Do not stop taking phentermine and topiramate without consulting with your doctor. If you suddenly stop taking phentermine and topiramate, you may experience seizures due to the Topiramate component, especially if you are at a higher dosage. Your weight loss physician will advise you to decrease your dose gradually and not stop suddenly.
Contra-indications for Phentermine and Topiramate
One can use oral contraceptives (birth control pills) to prevent pregnancy during your treatment with phentermine and topiramate. You may experience unusual spotting (unexpected vaginal bleeding) if you use this type of birth control. You will still be protected from pregnancy if you are spotting, but you can talk to your doctor about other forms of birth control if the spotting is bothersome.
Please let your weight loss doctor know if you are breast-feeding.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking phentermine and topiramate.
Phentermine and topiramate may slow your thinking and movements and affect your vision. Do not drive a car or operate machinery until you know how this medication affects you.
You are advised not to drink alcoholic beverages while you are taking phentermine and topiramate. Alcohol can make the side effects of phentermine and topiramate worse.
Phentermine and topiramate can prevent you from sweating and make it harder for your body to cool down when it gets very hot. Avoid exposure to heat, drink plenty of fluids and tell your doctor if you have a fever, headache, muscle cramps, or an upset stomach, or if you are not sweating as usual.
While the medication combination takes your interest in food, you should know that sometimes your mental health may change in unexpected ways and you may become suicidal (thinking about harming or killing yourself or planning or trying to do so) while you are taking phentermine and topiramate.
A small number of adults and children 5 years of age and older (about 1 in 500 people) who took antiepileptics such as topiramate to treat various conditions during clinical studies became suicidal during their treatment although this is rare. If you notice any significant mood changes or suicidal ideation, please talk to your doctor.
Drink extra fluids during your treatment with phentermine and topiramate.
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We offer FDA appetite suppressants or diet pills, such as Phentermine or Adipex, Qsymia, Belviq, Saxenda, Contrave, Bontril, Tenuate etc. We also offer very low calorie diets (VLCD),with optional and affordable insulin resistance.
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